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To further confirm the effect of GLP-1R on the central sensitization of CM, we examined the expression of CGRP and c-fos in the TNC

According to the Canadian Adult Obesity Clinical Practice Guidelines , bariatric surgery may also be an option for patients with poorly controlled type 2 diabetes and a BMI of between 30 kg/m 2 and 35 kg/m 2 , or in patients within that BMI range for whom optimal behavioural and medical management have been insufficient to produce significant weight loss

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I pledge to discourage public belittling of my colleagues, even when we disagree

46:2300-2307 Considine EG, Sherr JL