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Genetic differences in appetite signaling pathways, insulin sensitivity, and metabolic rate can explain why some people lose significant weight while others see minimal results

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patent describes new glucagon-like peptide 1 receptor (GLP-1R) agonists reported to be useful for the treatment of diabetes type 2, hyperglycemia and obesity.

GLP-1RA use also correlated with fewer systemic complications, including reduced risks of cellulitis, sepsis, acute kidney injury, dialysis initiation, and suicidal ideation or attempts

A new study suggests that the effectiveness of widely used GLP-1 weight-loss drugs may depend strongly on consistent use.

The gastrointestinal side effects of GLP-1 drugs are mediated by the brain, not the gut