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However, you should avoid taking doses too close together unless instructed by your healthcare provider

Comparative effectiveness of long-acting GLP-1 receptor agonists in type 2 diabetes: a short review on the emerging data

What does that mean for patients

Although it is possible that CRH may alter AGRP cellular activity independent of ionotropic induced changes in cellular activity, GLP1 effects on paraventricular hypothalamic nucleus CRH neurons may rely more heavily on modifying activity at target nuclei outside of the arcuate nucleus (Liu et al., 2017)

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