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The best results happen when the medicine is used along with healthy eating and exercise, and people may gain weight back if they stop taking the medicine

However, in the preplanned subgroup analysis looking only at patients who were or were not taking SGLT2 inhibitors or GLP-1RAs, the average difference in peak VO2 between the AT-001 group and the placebo group was 0.64, which was both statistically and clinically significant, Januzzi said

Obesity and type 2 diabetes (T2D) are associated with increased rates of mental disorders, particularly depression, anxiety and binge-eating disorder

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