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Some things to know: If you have a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2, semaglutide and tirzepatide may not be right for you

And tirzepatide with niacinamide is being explored for its potential to mitigate certain side effects

Lyndsey was my nurse, and she was amazing

Boxed warning context

If shedding coincides with the most aggressive dose escalation or the steepest weight-loss phase, your prescriber may consider pacing changes while keeping your broader goals on track

This suggests that for many people, 10 mg represents the point of diminishing returns, where side effects increase more than benefits