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Nevertheless, the research and development of GLP-1R agonists provide new perspectives and strategies for the treatment of diabetes, obesity, and related complications

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Potential long-term pancreatic risks: recurrent pancreatitis chronic pancreatic inflammation pancreatic exocrine insufficiency increased diabetes risk possible pancreatic fibrosis Though evidence is still evolving, ongoing inflammation could contribute to long-term pancreatic dysfunction

The following compounds were purchased from MilliporeSigma: Metformin (PHR1084), Lopinavir (SML1222), Quinine hydrochloride dehydrate (Q1125), and Fluoxetine (F132)