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Yes, you will lose weight on semaglutide without changing your diet and lifestyle, and your health will likely improve significantly

This article was medically reviewed by Michael Wasef, MD, a board-certified internal medicine physician at Wasef Health, PC, for clinical accuracy and compliance with current guidelines

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Patients with high blood pressure, heart disease, anxiety, sleep issues, medication interactions, or complex health histories should speak with a provider before considering tesofensine or any weight loss medication

Never stop prescribed medications without medical advice, as abrupt discontinuation may lead to symptom recurrence or rebound effects

ClinicalTrials.gov lists active TRIUMPH sites