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After a reviewing the evidence from non-clinical studies, clinical trials, and data from post-marketing surveillance, The European Medicines Agency (EMA) committee concluded that NAION is associated with use of semaglutide (the active ingredient in Ozempic and Wegovy)

The noticeable drop in GLP-1 receptor levels suggests that the tumor-suppressive role of GLP-1 may be mediated through the cAMP/PKA pathway

doi:10.1007/s00125-020-05196-3 34

La interaccin recproca entre ambas hormonas refleja una regulacin coordinada del equilibrio energtico, evidenciando que el GLP-1 no responde nicamente a la glucosa, sino al estado metablico integral del organismo (1)

Other forms may be 12:12 or 14:10