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Your patient's Raynaud's-type symptoms are most likely caused by the combination of carvedilol (non-selective beta-blocker) and phentermine (sympathomimetic)...

A once-weekly injectable glucose-dependent insulinotropic polypeptide/GLP-1 dual agonist conferred up to 14.7% weight loss at 13 weeks for adults with overweight or obesity, according to findings from the VENTURE trial published in Obesity