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In addition, GLP-1 analogs lead to improvements in brain glucose metabolism and glucose transport across the bloodbrain barrier in Alzheimers disease
2224 As a result, GLP-1 RAs are contraindicated for patients with a personal or family history of MTC or those with multiple endocrine neoplasia syndrome type 2
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Around 10% of Medicare enrollees, the officials said, will be eligible for coverage under those criteria

Neuroscience (2014) 277:613

Step therapy programs may require patients to first try lower-cost medications or demonstrate unsuccessful weight-loss efforts before qualifying for GLP-1 coverage
