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These findings point to broader experimental uses beyond diabetes models

Mounjaro Mounjaro contains tirzepatide, a dual GLP-1 and glucose-independent polypeptide (GIP) agonist that is thought to enhance its effects on weight loss and blood sugar control

23-25 Despite those studies showing an overall long-term benefit of tight sugar control in preventing worse retinopathy, a small percentage of subjects had a paradoxical early worsening seen in the first year

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1-in-3 GLP-1 users say they are eating out less often as a result of being on the drugs

GLP-1 agonists may be used alone in patients intolerant of metformin or in combination with metformin, thiazolidinediones, and sulfonylureas (or in any combination thereof)