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In short: GLP-1/GIP therapies improve body composition , helping you lose fat while maintaining and often improving your lean-mass ratio and muscle function

Takahashi and Yamanaka, 2016

Although several insulin-stimulating hormones are secreted in the gut, there are only two physiological incretins so far, including glucagon-like peptide-1 (GLP-1) and glucose-dependent insulin-stimulating peptide (GIP)

of water and drink immediately before, during or after a workout

The honest take: Bupleurum has less robust clinical data than the other ingredients in this formula

But something else happened less than a week into 2026 a change that may significantly change those sales figures this year, even while demand for the weight-loss and diabetes drugs explodes