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(Migraines are considered chronic when someone has a headache on 15 or more days a month for at least three months.) The researchers divided the participants into two groups: Those who started taking a GLP-1 medication for another condition (such as type 2 diabetes or obesity) within a year of being diagnosed with chronic migraines, and those who started taking topiramate (a prescription medication used to prevent migraine headaches) during the same period

Both GIP and GLP-1 are primarily secreted by enteroendocrine cells within the intestines after nutrient ingestion

However, behavioral therapies such as contingency management, cognitive-behavioral, and motivational enhancement therapies, are only moderately effective

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