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Weight loss itself improves acid reflux over time because excess body weight increases intra-abdominal pressure, pushing stomach acid upward

Results can be seen within a few weeks, with ongoing improvements as the program continues

Females of Reproductive Age: Inform females that treatment with JANUMET may result in ovulation in some premenopausal anovulatory women which may lead to unintended pregnancy [see Use in Specific Populations (8.3)]

Programs with fast support prevent treatment abandonment

Aim for 80 to 100 grams of protein daily, distributed across 4 to 6 meals