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It's also worth noting that semaglutide may delay gastric emptying, which could theoretically affect the absorption of some oral medicines, though this is likely of minimal relevance to melatonin

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They work by mimicking a hormone that targets areas of the brain regulating appetite, thus reducing hunger and leading to significant weight loss

Also, because patients were not blinded to the change in their dose frequency, they might have made other changes in their lives to influence their weight and metabolic measurements during the study period

None of it is a prescription, a treatment recommendation, or medical advice