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[DOI] [PMC free article] [PubMed] [Google Scholar] 371.Que Q, et al

However, SCFA-induced increases in PYY secretion should not be overlooked because PYY has a strong bone resorption-promoting effect

The cost to Medicare of covering obesity drugs under Part D has been estimated at between $25 billion and $35 billion over 10 years, which could have been a driving factor in the reluctance or unwillingness of major Part D plan sponsors to participate in the BALANCE model as it was originally designed

As access expands, demand grows further

Even more affordable compounded versions represent a significant monthly expense for many households

The clinical use case still needs to be proven
