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Incretin levels and effect are markedly enhanced 1 month after Roux-en-Y gastric bypass surgery in obese patients with type 2 diabetes

The study found that the risks of these adverse outcomes was similar with or without GLP-1 exposure during the first trimester

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In terms of GLP1related mechanisms that might affect vulnerability to or development of AUD, a genetic study composed of four human genetic association studies has shown that the GLP1 receptor 168Ser allele is associated with increased alcohol selfadministration and a higher fMRI bloodoxygenleveldependent (BOLD) response in the globus pallidus when receiving rewarding feedback in the monetary incentive delay task