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Topiramate must never be stopped abruptly, as sudden withdrawal risks rebound seizures or status epilepticus in people with epilepsy

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Before injecting, participants should: Wash hands thoroughly with soap and water Allow the device to reach room temperature (if stored in the fridge) for the time specified in the trial instructions typically around 30 minutes, though this may vary by device Inspect the solution it should be clear and colourless

The FDA highlights important safety considerations, including a boxed warning related to thyroid Ccell tumors