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Improving function and survival of pancreatic islets by endogenous production of glucagon-like peptide 1 (GLP-1) Proceedings of the National Academy of Sciences of the United States of America

JAMA 2015
While hot flashes alone are generally not dangerous, certain circumstances warrant prompt medical evaluation to ensure patient safety and rule out alternative diagnoses that may require specific intervention

Clinical trials report up to 22.5% body weight loss over 72 weeks

It has been shown that obese women have a lower LH amplitude and mean serum level of LH, which might result in abnormal ovarian follicular recruitment and development, which causes longer follicular phases indicating ovulatory problems [86,111]
