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While evidence supports behavior modification, compounded GLP-1 medications may address metabolic factors that behavioral interventions alone cannot target

In this review, we summarize the state-of-the-art evidence regarding the epidemiology and pathophysiology of diabetic HFpEF, and the landscape of the novel antidiabetic drugs in the treatment of diabetic HFpEF, as well as discuss the relevant mechanisms, aiming to broaden the understanding of diabetic HFpEF and gain new insight into the treatment of this disease

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Excitingly, researchers are now investigating the possible use of GLP-1 based therapeutics for diseases beyond Type 2 diabetes and obesity