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2024 doi: 10.2337/dci24-0003

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Not only the protection of the integrity of the blood-brain barrier, this whole neuroglial vascular unit, the myelin sheath protection, reducing inflammation within the brain, improving the glymphatic flow, which is of course critical for clearing waste and promoting cerebral vascular remodeling and more, so the brain effects here is what it seems to be

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At the time, the approval was seen as a major step forward for diabetes care

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The GIP component enhances insulin secretion in response to meals while also appearing to buffer some of the nausea commonly associated with GLP-1 activation

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Strategies to preserve muscle mass, including resistance exercise and adequate protein intake, would be important considerations

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Patients treated with GLP-1 agonists often experience weight loss as a side effect of the drug

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