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2024 doi: 10.2337/dci24-0003

Not only the protection of the integrity of the blood-brain barrier, this whole neuroglial vascular unit, the myelin sheath protection, reducing inflammation within the brain, improving the glymphatic flow, which is of course critical for clearing waste and promoting cerebral vascular remodeling and more, so the brain effects here is what it seems to be

At the time, the approval was seen as a major step forward for diabetes care

The GIP component enhances insulin secretion in response to meals while also appearing to buffer some of the nausea commonly associated with GLP-1 activation

Strategies to preserve muscle mass, including resistance exercise and adequate protein intake, would be important considerations

Patients treated with GLP-1 agonists often experience weight loss as a side effect of the drug