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Acid denatures them, pepsin cleaves them, trypsin finishes the job

Starting above 2mg dramatically increases the probability of nausea severe enough to compromise nutrition and cause early dropout

AGEs react with amino acid residues in proteins, forming irreversible modifications that negatively affect sperm, including reduced sperm count, decreased motility, increased morphological abnormalities, residual histones, fish sperm protein deficiency, sperm DNA fragmentation, decreased antioxidant capacity in the testes, and elevated levels of receptor for advanced glycation end products (RAGE) and carboxymethyl lysine (CML) proteins [160]

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