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Effects of GLP-1 Receptor Agonists on RAAS GLP-1 receptor agonists (GLP1-RA) are a relatively novel class of anti-diabetic drugs that improve glycemic control by potentiating the physiological effect of the gut hormone GLP-1 (59)

The indication is to effectively reduce glycosylated hemoglobin levels in patients with T2DM by reducing fasting and postprandial blood glucose levels (61, 62)

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Potential improvements in fat content and glucose production might also occur in the liver as a result of GLP-1's impact [37]