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Hormonal shifts (like menopause), inflammation, or even a salty meal can cause temporary water retention that masks fat loss

Even modest weight loss (510% of body weight) can improve metabolic hormone dynamics

Other At-Risk Groups GLP-1 medications are generally not suitable for individuals with severe gastrointestinal disorders like gastroparesis, those with type 1 diabetes (as these drugs are approved only for type 2 diabetes and obesity), and people with a history of suicidal thoughts, active eating disorders, or heavy alcohol use

In fact, JWU-A021 raised the [Ca 2+ ] i in fura-2 loaded STC-1 cell monolayers (Fig

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