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[34] [35] In the brain, they act on satiety centers to reduce appetite and food intake

Wang, M
The primary objective of the study was to demonstrate that orforglipron is superior to placebo in body weight reduction from baseline after 72 weeks

doi: 10.1056/NEJMoa1603827 14 MarsoSPBainSCConsoliAEliaschewitzFGJdarELeiterLAet al

Individual results vary significantly based on factors including starting weight, adherence, diet, exercise, genetics, and overall health status

While evidence is not definitive for UTI prevention specifically, the dual benefit makes them a reasonable addition for semaglutide users
