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The delayed gastric emptying primarily affects how quickly drugs are absorbed rather than the total amount absorbed, which may explain why clinically significant interactions are less common than initially feared

The side effect profile of cagrilintide is noteworthy

2022;12 doi: 10.3389/fonc.2022.976262

Researchers looked at the health records of 95,490 people in Sweden, 81 per cent of whom had anxiety, 55 per cent had depression and 36 per cent had both conditions

However, CMS clarified in a memo dated March 20, 2024, that anti-obesity medications that receive FDA approval for an additional medically accepted indication can be considered a Part D drug for that specific use. As of August 19, 2024, the only GLP-1 RA this applies to is Wegovy, which, in addition to its obesity indication, is also indicated to reduce the risk of major adverse cardiovascular events in adults with established cardiovascular disease and either obesity or overweight

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