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7 Several studies have also demonstrated the integral role that the glucose portal sensor plays in glucose homeostasis, and the association of GLP-1Rs in portal glucose sensing where GLP-1 is required for portal glucose to stimulate insulin response

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Recent Clinical Study of Microneedle Patch for Skin Aging Treatment The concept of microneedles was proposed in the 1970s, 69 but it was not until the 1990s that the microelectronics industry provided the microfabrication tools necessary to create these small structures, allowing for experimental validation