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In both mice and rats, administration of ICV exendin-4(939) (Ex9), a potent GLP-1r antagonist, during oral glucose impairs glucose tolerance and reduces insulin levels (104, 209, 229)
That is not a modest improvement

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The science of why you might want to kick your diet soda habit Diet sodas have long been marketed as weight loss tools

doi: 10.3389/fnmol.2018.00002
