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Both sexes are subject to the neurochemical effects on reward pathways, but hormonal factors create different clinical presentations
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Hyperactive intracellular calcium dynamics in B lymphoblasts from patients with bipolar I disorder

doi: 10.1056/NEJMoa2107519 197 AbdallaMADeshmukhHAtkinSSathyapalanT

Evidence on longer-term effects, beyond two years, was more limited

The ruling also reinforces the administration's authority to terminate other TPS designations currently under review