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This structure contains exceptionally high concentrations of GLP-1 receptors and appears to play a crucial role in mediating the reward-modulating effects of GLP-1 agonists

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While GLP-1R is solidly expressed in the pancreatic - and -cells, most studies report absence [[397], [398], [399]] or very restricted expression of GLP-1R in a small subset ( 6.6 mM [82,480]

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