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doi:10.1530/eje.0.1460863 Lee S, Lee DY

This highlights a gap in the research, as PsA has been less extensively studied with GLP-1RAs, and further studies are needed to confirm whether GLP-1RAs provide similar immunomodulatory and metabolic benefits in PsA as they do in PsO

Tirzepatide (Mounjaro for diabetes, Zepbound for weight loss) activates two receptors GLP-1 and GIP which is why it tends to produce somewhat stronger weight-loss results on average

In March 2024, the Warnings and Precautions section for doctors in the monograph for Ozempic was updated to state that the Use of GLP-1 receptor agonists may be associated with severe gastrointestinal disease and that Events of delayed gastric emptying, dysgeusia and ileus have been reported

These combined effects make GLP-1 receptor agonists particularly valuable for patients with type 2 diabetes who are overweight or obese

Plus, the added stigma of being a man with an eating disorder meant it took him a long time to admit to himself, and then to his therapists