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Maintain appropriate physical activity
Comparatively, 32,336 GLP-1 receptor agonists and 96,212 SGLT-2 inhibitor users were followed for a median of 1.2 and 1.2 years, respectively

Lancet Diabetes Endocrinol 2025;13:374383 [DOI] [PMC free article] [PubMed] [Google Scholar] 300

It is injected once weekly at doses ranging from 0.25 mg (starting dose) to 2.0 mg (maximum dose for diabetes)

The combination of liraglutide and anti-PD-1 can enhance the cytotoxicity of CD8 + T cells and induce immunity to tumor rechallenge in Hepa16 allograft mice ( pos CD3 + T cells treated with exendin-4 secreted less IFN-, exhibited weaker migration ability, and upregulated genes related to apoptosis, immunoregulation, and immune deficiency, such as CASP3 and CASP7

The results suggested that GLP-1 agonists use was associated with lower mortality (both all-cause and cardiovascular mortality) compared with DPP-4 inhibitors or placebo or no treatment
