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[DOI] [PMC free article] [PubMed] [Google Scholar] 37.Buse J.B., Rosenstock J., Sesti G., Schmidt W.E., Montanya E., Brett J.H

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Leptin levels also drop significantly as fat mass decreases, signaling to your brain that energy reserves are depleted and conservation is necessary

Noyan-Ashraf MH, Shikatani EA, Schuiki I et al (2013) A glucagon-like peptide-1 analog reverses the molecular pathology and cardiac dysfunction of a mouse model of obesity