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For some people, these medications can serve as a valuable adjunct to lifestyle change helping to enhance weight loss and metabolic outcomes when used appropriately

In this infographic, Ive outlined the mechanistic interplay between these two modalities: The ketogenic diet reduces glycemic load and insulin demand, promotes fat oxidation, and enhances mitochondrial function

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Key Takeaways Clinical trials indicate that retatrutide typically results in more rapid and significant weight loss than semaglutide, particularly during the early and midterm stages of treatment