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Authorization outcomes

6668 X-ray crystal structures of exendin-4 and GLP-1 bound to the isolated NTD of GLP-1R confirmed the multidomain binding model in detail

N Engl J Med 361:4051

The observed magnitude of medication effects on heavy drinking, said the team, while preliminary, is promising especially considering the effect sizes observed for FDA-approved AUD treatments, and are also notable in that they were obtained at the two lowest doses of semaglutide used clinically

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