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These biological medications contain delicate peptide molecules that degrade when exposed to inappropriate temperatures

Standard diabetes care includes periodic comprehensive reviews, during which clinicians should remain alert to symptoms suggesting thyroid dysfunction and arrange appropriate investigations when clinically indicated rather than following a protocol of routine screening

Semaglutide acts on one receptor (GLP-1), while tirzepatide acts on two (GLP-1 and GIP)
Broader Medicare coverage begins mid-2026, with full implementation by January 2027
Retatrutide does not currently hold a marketing authorisation from the MHRA or EMA and is not available on the NHS