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Ozempic in managing Type 2 diabetes, from mechanisms of action to side effects, cost, and coverage.

Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are two gut hormones, defined incretins, responsible for the amplification of insulin secretion after oral glucose intake

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In addition to outcomes data, payers will be guided by cost-effectiveness considerations, e.g., as assessed by European HTA bodies or ICER, with implications for drug prices to meet acceptable cost-effectiveness thresholds