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Your eGFR establishes where your kidneys are functioning before treatment begins

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doi: 10.2337/dc14-1952
Protocol: Do not panic

SOUL has enrolled around 9640 patients with T2D and cardiovascular disease, cerebrovascular disease, symptomatic peripheral artery disease, or chronic kidney disease for 3.55 years [55]

This observation could be explained by its known role on central receptors in the regulation of food intake, independent of its effects on gastrointestinal motility
