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GLP-1 inhibits food intake and promotes satiety in healthy individuals and those with obesity and diabetes [33]

For rheumatoid arthritis, they are not replacements for your DMARD or biologic but the 2025 research from centers like UCLA suggests they can be a powerful complement: less disease activity, fewer flares, lower inflammation markers, better cholesterol and blood sugar, and reduced cardiovascular risk sometimes even at low doses

A human study showed that GLP-1 significantly delayed gastric emptying but did not affect gastric muscle contractility or water homeostasis, suggesting GLP-1 inhibits gastric emptying through an indirect mechanism rather than altering muscle contractility directly [121]

In the habituation stage, mouse was placed in an acrylic-made open square arena (48 48 cm) and allowed to freely explore for 5 min

Kellerer et al., 2022