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Industry Analysis Published: December 22, 2025 Content Category: Dietary Supplements - Weight Management Regulatory Framework: DSHEA supplement regulations, FTC endorsement guidelines, FDA dietary supplement guidance Target Market: New Year 2026 Weight Loss Season

No head-to-head trials comparing agents in these two classes are currently available to guide decision-making

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Employers continue to need access to less expensive options to effectively treat obesity

-: Novo Nordisk has released new #Phase 3 data (sub-analysis of the #REDEFINE-1 trial) for cagrilintide, a long-acting #amylin analogue (2.4 mg weekly), used as #monotherapy in people with obesity or overweight plus a #weight-related comorbidity (excluding type 2 diabetes)

Diabetes Care (2020) 44(Supplement_1):S111S24