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Zaher Merhi, publicado en Fertility and Sterility Reports , revisa varios estudios preclnicos que evalan el impacto de estos frmacos sobre la funcin ovrica y uterina en modelos animales

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In the STEP trials, semaglutide was administered as part of a comprehensive lifestyle intervention that included a reduced-calorie diet (approximately 500 kcal/day deficit based on baseline energy requirements) and a minimum of 150 min of physical activity per week [38,39,40,41,42,43,44,45,46, 78, 97]