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GLP-1 RAs have been found to improve overall cardiovascular health and reduce major adverse cardiovascular events (MACE) by improving the endothelial function of the vasculature and lowering ANP (atrial natriuretic peptide) production, leading to reduced blood pressure
However, genetics, hormones, and age dictate where your body holds onto its final stores of fat

Novo Nordisk filed for FDA approval of CagriSema in early 2026, with a review decision expected later this year

Diabetes Care (2019) 42(9):172432
But heres what its important to know: semaglutide amplifies a pathway
