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This means a single molecule activates two hormone receptors involved in appetite and weight regulation: GLP-1 receptors , which help control blood sugar and reduce appetite Amylin receptors , which slow how quickly food leaves the stomach (known as delayed gastric emptying) and increase satiety (feeling full and satisfied after a meal) Many GLP-1 weight loss medications, including Wegovy, Saxeda and Ozempic, only target GLP-1 receptors

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Thresholds derived from Phase 2 dose-response data and tissue-specific glucagon receptor pharmacology