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Retatrutide produces the greatest weight loss (up to 24.2%), followed by tirzepatide (up to 22.5%), then semaglutide (up to 14.9%), but retatrutide remains i...

My take: GLP-1RAs may become more than metabolic drugs, but oncology needs prospective cancer-outcome data before calling this prevention

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households are now using GLP-1s.* New patient prescriptions for GLP-1 medications increased by 2.9 million from September 2024 to September 2025, a 16% lift

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