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Description
Most patients experience symptom resolution within 48 weeks as their gastrointestinal tract adapts

doi: 10.2337/dc16-0690 57 MathieuCZinmanBHemmingssonJUWooVColmanPChristiansenEet al
People with leptin gene mutations are obese secondary to pronounced hyperphagia [84], and satiety and body weight can be regulated in people with these genetic mutations with leptin treatment [85]

Learning to recognize and respect these new, sometimes more subtle, signals of fullness is essential

Funding None to disclose

Cellular cAMP determination assay Freshly isolated CSMCs were cultured in DMEM supplemented with 10% FBS, 100 U/mL of penicillin, and 100 g/mL of streptomycin at 37 C in 5% CO 2
