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This hormonal shift can trigger a range of symptoms: Hot flashes and night sweats Mood swings or irritability Sleep disturbances Vaginal dryness Changes in metabolism and fat distribution Reduced estrogen also impacts how your body handles fat and insulin, the hormone that helps control blood sugar

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Front NeuroSci 13:629 [DOI] [PMC free article] [PubMed] [Google Scholar] Griffith CM et al (2018) Evidence for altered insulin receptor signaling in Alzheimers disease

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Declining estrogen during menopause can also contribute to gradual losses in muscle mass and strength over time

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