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Researchers have also observed that glutathione regulates protein function through reversible S-glutathionylation of cysteine residues, modulating the activity of signaling proteins, transcription factors, and metabolic enzymes in response to oxidative conditions

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After its synthesis, GSH is transported to the intracellular compartments, mitochondria, endoplasmic reticulum and nucleus, but most of it is released through transporters toward the extracellular space

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