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This matters most in groups already vulnerable to changes in bone density, including: Post-menopausal women Adults over 50 Individuals with low resistance training exposure Athletes experiencing chronically low energy availability GLP-1 therapy is not contraindicated for these groups

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This review study analyzes human and animal trials of various GLP-1 medications for their role in addressing the hallmarks of aging, such as mitochondrial function and oxidative stress, including low-dose protocols via injection for Parkinson's patients on exenatide