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Notably: HbA1c improvement did not mediate cancer risk reduction Data are from first-generation GLP-1snewer agents like tirzepatide werent included Long-term adherence and treatment durability still need clarification Bottom line: GLP-1s may be approaching BMS in long-term cancer prevention for people with diabetes and obesity

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2025;45(4):e16132

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Access and coverage are key hurdles

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Summary of Table 2 Benchmarks The metrics in Table 2 serve as benchmarks for performance : e.g., an average specialty fill rate of 62% ( [12] ) or a first-pass GLP-1 approval of ~30% ( [3] )

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