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(2.8 to 4.2 kg) of weight loss has been reported with GLP-1 agonist use

GLP-1 medications are biologic peptides that require specific storage conditions to maintain their structural integrity and therapeutic effectiveness

In addition, Ex-4 provides neuroprotection against ischemia-induced damage in the hippocampus by downregulating hypoxia-inducible factor-1 and modulating apoptosis through the increased B-cell lymphoma 2 (Bcl-2)/Bcl-2-associated X-protein (Bax) ratio, which is mediated by the GLP-1 receptor [48]

2024 Jan;30(1):168-176

I see people arguing that because we have not seen a clear increase in aspiration events, there is no need to treat these patients differently

Semaglutide : Injectable (Ozempic/Wegovy) requires weekly subcutaneous injection